San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years removed from his playing days for the Cyclones.

The 49ers QB became a better vocal leader this offseason. How will that help him overcome injuries to Deebo Samuel Sr. and Christian McCaffrey?

In Purdy's last seven starts, he has won four games, lost three, thrown six touchdown passes and six interceptions, fumbled once and posted a passer rating of 87. That's about as average as it gets. And he's playing on the best team in football.

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 49ers vs. Rams game.

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed practice with a sore hamstring. The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday's practice.

George Kittle could have to miss his first game of the season as the San Francisco 49ers take on the Los Angeles Rams on Sunday. Per ESPN's Adam