Is this the week that San Francisco 49ers running back Christian McCaffrey returns ... though they initially held off on that ...

San Francisco 49ers running back Christian McCaffrey finally made his season debut on Sunday, rushing for 39 yards on 13 ...

San Francisco treaded water without Christian McCaffrey. Now that the NFL's reigning Offensive Player of the Year is back, it ...

The 49ers did not exactly ease Christian McCaffrey back into the action. Instead, he hit the ground running. After playing ...

The 49ers are coming off their bye and kicking off the second half of their season at the Buccaneers on Sunday. Don't let ...

San Francisco 49ers star running back Christian McCaffrey was activated from injured reserve on Saturday and will make his ...

McCaffrey went on injured reserve on Sept. 14 and has remained there for nearly two months before his activation Saturday. Through a time that McCaffrey described Friday as "tough," he has gone ...

Advertisement But for the first time this season, the 49ers had Christian ... But when McCaffrey sprinted out of the backfield, slowed down with a hop, and then took off again, David was toast.

But the week off also brought an increasing level of excitement for the 49ers... San Francisco 49ers head coach Kyle Shanahan ...

San Francisco 49ers running back Christian McCaffrey takes off up the middle for a 27-yard run on the 49ers' opening drive vs. the Seattle Seahawks. Watch highlights from the Week 9 matchup ...

San Francisco 49ers star running back Christian McCaffrey was listed as questionable on Friday's injury report and is ...