Margaret Qualley put blood, sweat and tears into her celebrated performance in The Substance, so much so that it took her a year to physically recover from her intense prosthetics. On the January 13 episode of Josh Horowitz's podcast Happy Sad Confused,

In 'The Substance,' Margaret Qualley wore a mountain of facial prosthetics, which had a detrimental effect on her face.

Margaret Qualley really felt the effects of “The Substance.” The actress, 30, recently appeared on Josh Horowitz’s “Happy Sad Confused” podcast and spoke about how wearing extensive prosthetics to shoot the bloody horror film took a toll on her skin.