Hormone receptor structure reveals how it functions in heart disease
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor ...
eLife7h
Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8
The compelling evidence explains how Rab8 family members bind at two sites to allosterically regulate MICAL1, and relieve an auto-inhibited state unable to bind actin. This study lays the basis for ...