Aiyuk missed most of training camp due to a hold out, so a slow start isn't a huge surprise. Now, in Week 3, he should be up to speed and he gets a defense that has been pretty awful so far. The Rams ...

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...

With stud wide receiver (and quasi-backup running back) Deebo Samuel Sr. out in Week 3, San Francisco will continue to lean on Mason in a divisional matchup against the Rams. It's a smash opportunity ...

After an encouraging performance in Week 1, the Rams (0-2) got something of a wake-up call in the 41-10 loss to the Cardinals ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

San Francisco 49ers defensive coordinator Nick Sorensen, offensive line/run game coordinator Chris Foerster, and quarterback ...

Although the Rams-49ers rivalry has been decidedly tilted in San Francisco's direction in recent years, the games have still been must-see spectacles.

The Los Angeles Rams need top draft picks Jared Verse and Braden Fiske to come up big Sunday against a 49ers’ squad that ...

San Francisco 49ers wide receiver George Kittle received a notable practice update on Thursday ahead of Week 3's Rams matchup ...

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

The retirement of Aaron Donald has shifted the landscape, pushing both the 49ers and Rams to adapt their strategies for an ...