What is The Substance? It's a drug that will create a younger version of you from your own DNA. That new you will graphically fall out of your back, complete with squishy sound effects.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

Since its Cannes premiere “The Substance” has churned controversy over its body horror scenario, frequent, flagrant nudity – and buzz about a Best Actress Oscar nomination for Demi Moore.

Coralie Fargeat’s bloody-as-hell satire lets the star flip the bird to showbiz’s youth obsessions and beauty double standards — in the best (and grossest) way imaginable

When it comes to upcoming horror movies, one of this year’s best may be hitting theaters this weekend, with Demi Moore ’s body horror flick The Substance causing quite a stir amongst critics since its premiere at Cannes.

"The Substance" is a dark modern fable that starts out blaming men for reducing women to sex objects and then cuts deeper. Fargeat saves a special rage for women who conspire in their own diminishment, trading their soul in a pulse beat for a few more shining hours as a goddess.

Coralie Fargeat’s sci-fi shocker follows the downward spiral of a 50-year-old movie star who resorts to drastic measures

Demi Moore’s new film “The Substance” recently received a 13-minute standing ovation at Cannes, proving her worth as one of the most decorated actresses in Hollywood. Moore was also mentioned by Variety and People magazine as a sure nominee for the Oscars 2025.