RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

Coach Kyle Shanahan said Guerendo (foot/hamstring) will be limited at Thursday's practice, Cam Inman of The San Jose Mercury News reports. As Shanahan projected Monday, Guerendo is returning to the ...

Reporting emerged earlier on Thursday noting that 49ers running back Isaac Guerendo is unlikely to play in Sunday's game ...

The San Francisco 49ers are poised to unveil their fourth starting running back of the season Sunday. The latest next man up ...

The San Francisco 49ers had a fatal flaw in their draft strategy during the Kyle Shanahan-John Lynch Era.

The 49ers need bodies. That's why they just signed offensive tackle Charlie Heck of the Arizona Cardinals practice squad.

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo injury updates and return date for Week 17 (2024).

Guerendo (foot, hamstring) has been ruled out for Sunday's game at Miami, Matt Maiocco of NBC Sports Bay Area reports. Guerendo didn't practice this week and thus appears in danger of missing time ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

Isaac Guerendo faces an uphill climb if he wants to suit up on Sunday vs. the Dolphins after suffering a hamstring injury ...

The injury updates from San Francisco 49ers head coach Kyle Shanahan on Monday weren't all bad. Shanahan in a conference call ...

The rookie running back did not practice last week and has been officially ruled out of Sunday’s clash at Hard Rock stadium ...