The study will measure the proportion of pregnancies without intrauterine transfusion, hydrops fetalis, or fetal loss/neonatal death. Phase 3 of the AZALEA study, the first placebo-controlled, ...

FNAIT may occur when paternally inherited human platelet antigens (HPAs) on the surface of fetal platelets are incompatible with those of the mother and recognized as foreign by the mother’s immune ...

Standard nutritional recommendations to ensure a healthy pregnancy for both mother and baby also apply to pregnancies affected by FNAIT.

Which of the statements below about the clinical features of Friedreich ataxia (FA) are correct? Select one of the options for each question, then submit your answers to see how well you scored and ...

Necrotizing and crescentic glomerulonephritis arises in all 3 AAV subtypes: GPA, MPA, and EGPA. According to findings from a study recently published in the journal Kidney International, among ...

HPA genotyping is an important investigation in assessing the underlying cause of a neonate presenting with severe thrombocytopenia. A 34-year-old female (gravida 6, para 4) presented at 31 weeks of ...

Internationally, next to matching for D, matching for K and other Rh antigens (C, c, E, and/or e) is often applied to prevent HDFN, and "cEK matching" has been strongly advocated in The Netherlands ...

As a patient with alpha-1 antitrypsin deficiency (AATD), I didn’t always have an aversion to strong scents. In fact, I enjoyed having perfumes and scented candles as a teenager. However, now that I’m ...

Findings of recent studies confirm an effect of the disease on skeletal muscles and support the idea that of progressive mitochondrial damage drives the progression of the disease. The effects of ...

Dendritic swelling counts were more robustly correlated with torpedo counts in Purkinje cells. Dendritic swellings range between 1 in 1000 and 42 in 1,000 Purkinje cells across cerebral degenerative ...

The MRI also detected abnormal vessels in the perimedullary region of the cervical spinal cord and the left petrous apex. The set of differential diagnoses for neuromyelitis optica spectrum disorder ...

The clinical presentation of FNAIT also varies from very mild, asymptomatic thrombocytopenia to very severe lCH that can be lethal or cause lifelong neurological problems. Other clinical features of ...