A big cat sanctuary in Washington is temporarily closed and quarantined after bird flu killed 20 wild cats there, including cougars, bobcats and a tiger.

Twenty big cats, including a half-Bengal tiger and four cougars, died between late November and mid-December at a sanctuary in Washington State after becoming infected with bird flu, according to the facility’s director.

Bird flu has been on the rise in Washington state and one sanctuary was hit hard: 20 big cats – more than half of the facility’s population – died over the course of weeks.