Los Angeles Rams coach Sean McVay is "not sad" he doesn't have to game plan for San Francisco 49ers stars Deebo Samuel and ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

San Francisco 49ers quarterback Brock Purdy spoke about orchestrating the team's offense without playmakers Christian McCaffrey and Deebo Samuel.

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

Samuel (calf) won't practice Thursday, Jennifer Lee Chan of NBC Sports Bay Area reports.

The San Francisco 49ers will be missing two of their biggest playmakers when they visit SoFi Stadium on Sunday to face the ...

Check out our Rams vs. 49ers how to watch guide to learn when they play and what free live streams are available ahead of ...

The spread has moved one point in the Rams’ direction since Monday, likely because of the 49ers’ recent injury news ...

The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...