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Archives of Disease in Childhood is an international peer review journal that aims to keep paediatricians and others up to date with advances in the diagnosis and treatment of childhood diseases as well as advocacy issues such as child protection.
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2 days ago · Archives of Disease in Childhood is led by Dr Nick Brown, clinician, epidemiologist and international child health expert. His vision is to enhance child health through training, advocacy, and publishing high quality research that will influence policy, and to do all this “with passion, wit and flavour”.
What’s new in the management of neonatal early-onset sepsis?
The expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they ...
Survival and unique clinical practices of extremely preterm infants ...
Objectives To investigate prognosis and clinical practices of infants born at 22–23 weeks’ gestational age (wkGA) in Japan. Design A national institutional-level electronic questionnaire surveys performed in September 2021. Setting All perinatal centres across Japan. Patients Infants born at 22–23 wkGA in 2018–2020. Main outcome measures Proportion of …
Management and investigation of neonatal encephalopathy: 2017 …
This review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE). Encephalopathy in neonates can be due to varied aetiologies in addition to hypoxic-ischaemia. A combination of careful history, examination and the judicious use of investigations can help ...
Neonatal thrombocytopenia: causes and management
Neonatal thrombocytopenia is a common clinical problem. Thrombocytopenia presenting in the first 72 hours of life is usually secondary to placental insufficiency and caused by reduced platelet production; fortunately most episodes are mild or moderate and resolve spontaneously. Thrombocytopenia presenting after 72 hours of age is usually secondary to sepsis or necrotising enterocolitis and is ...
Effect of probiotic supplementation on the gut microbiota in very ...
Objective There is increasing evidence that probiotic supplementation in very preterm infants decreases the risk of necrotising enterocolitis (NEC), sepsis and mortality. The underlying mechanisms, including effects on the gut microbiota, are largely unknown. We aimed to systematically review the available literature on the effects of probiotic supplementation in very preterm infants on gut ...
About | ADC Fetal & Neonatal Edition
The content of ADC Fetal & Neonatal is endorsed by the Royal College of Paediatrics and Child Health for Continued Professional Development in line with RCPCH CPD guidelines. ADC Fetal & Neonatal has an open access companion journal, BMJ Paediatrics Open.For information about the Editor-in-Chief and editorial team, please refer to the Editorial Board page.
Table of contents - ADC Fetal & Neonatal Edition
Apr 18, 2024 · Diagnosis and management of congenital diaphragmatic hernia: a 2023 update from the Canadian Congenital Diaphragmatic Hernia Collaborative (25 October, 2023) Free
Understanding the principle biophysics concepts of pulmonary …
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate structure of mammalian alveoli along with successive compression-expansion respiratory cycles. To do so, surfactant reduces dramatically surface tension at the air-liquid interface, an activity that depends critically on a proper lipid composition and the presence of some specific surfactant proteins. Lack ...